In late 1980s Los Angeles, Jacki and her all-girl punk rock band, Clam Dandy, are trying to make it big. On the verge of turning 40, Jacki decides that if the band's one last shot at the big time is unsuccessful, she will give up her dreams of stardom. Along the way, the women are rocked by personal tragedies that threaten to break up the band before they can get their last shot at success.